13C- mithacetin breath test for assessment of liver functional capacity
نویسندگان
چکیده
منابع مشابه
13C Methacetin Breath Test for Assessment of Microsomal Liver Function: Methodology and Clinical Application
Assessment of the liver function, and the need of constant monitoring of the organ's capacity, concerns not only patients with primary liver diseases, but also those at risk of hepatopathies secondary to other chronic diseases. Most commonly, the diagnostics is based on measurements of static biochemical parameters, which allow us to draw conclusions only indirectly about the function and the d...
متن کامل13C-methionine breath tests for mitochondrial liver function assessment.
13C-methionine breath test has been proposed as a non-invasive tool for the assessment of human hepatic mithocondrial function. Two methionine breath labeled with 13C in differents point of his molecular structure have been used for breath test analisys. Aim of this study was to compare two differently 13C-labeled methionines in the evaluation of mitochondrial oxidation in basal conditions and ...
متن کاملGender affects 13C-ketoisocaproic acid breath test.
BACKGROUND AND AIMS 13C-Ketoisocaproic Acid Breath Test (13C-Kica-BT) has been proposed to assess mitochondrial function. Aim of this study is to evaluate whether gender affects mithocondrial oxidation by means of 13C-Kica-BT in healthy subjects in basal conditions and after an acute oxidative stress induced by ethanol. METHODOLOGY 50 healthy volunteers were given 1 mg/kg of 13C-Kica together...
متن کاملEvaluation of 13C-phenylalanine and 13C-tyrosine breath tests for the measurement of hepatocyte functional capacity in patients with liver cirrhosis.
Liver disease is associated with an abnormal elevation of the plasma concentrations of the aromatic amino acids phenylalanine and tyrosine. The liver is the main site of aromatic amino acid metabolism, particularly the hydroxylation of phenylalanine to tyrosine and further tyrosine degradation. In the present study, we have examined the usefulness of the L-[1-13C]phenylalanine breath test (13C-...
متن کامل13C-breath tests for clinical investigation of liver mitochondrial function.
BACKGROUND Mitochondria play a major role in cell energetic metabolism; therefore, mitochondrial dysfunction inevitably participates in or even determines the onset and progression of chronic liver diseases. The assessment of mitochondrial function in vivo, by providing more insight into the pathogenesis of liver diseases, would be a helpful tool to study specific hepatic functions and to devel...
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ژورنال
عنوان ژورنال: World Chinese Journal of Digestology
سال: 2004
ISSN: 2219-2859
DOI: 10.11569/wcjd.v12.i11.2646